Multiplexed and Quantitative: NeuCoDIA

Minogue et al. (2015) recently published a multiplexed quantitative proteomics technique for data-independent acquisition (DIA).1 Using neutron-encoded (NeuCode) stable isotope labeling with amino acids in cell culture (SILAC), the team enabled a highly reproducible and quantitative 2-plex assay (NeuCoDIA) that identified between 85.9% and 95.4% of peptides. The principles behind DIA for mass spectrometry (MS)-based proteomics approaches Read the rest of this article

The post Multiplexed and Quantitative: NeuCoDIA appeared first on Accelerating Science.


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