Monoclonal Antibody Characterization Using Exactive Plus EMR Orbitrap mass spectrometer based SEC–MS

Commercial production of monoclonal antibodies (mAbs) from mammalian cell culture systems requires accurate characterization of products. In addition to pure antibody, the manufacturing process releases dimers and other mAb aggregates or fragments into the culture medium. These associated products can affect mAb function by interfering with product half-life, stability and activity. Therefore, in order to Read the rest of this article

The post Monoclonal Antibody Characterization Using Exactive Plus EMR Orbitrap mass spectrometer based SEC–MS appeared first on Accelerating Science.

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