Repurposing Existing Drugs to Combat Ebola Virus Infection

Following infection, the Ebola virus (EBOV) binds to cell surface proteins, then relies upon host factors to complete its lifecycle by internalization and trafficking through endosomal vesicles. Sakurai et al. (2015) present an elegant study revealing two-pore channels (TPCs) to be key players regulating this viral endosomal movement.1 The research team provides evidence that disrupting this pathway inhibits viral Read the rest of this article

The post Repurposing Existing Drugs to Combat Ebola Virus Infection appeared first on Accelerating Science.

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