Data acquisition and processing form the backbone of mass spectrometric (MS) proteomic analysis for accurate peptide identification and quantitation. The two strategies currently used in MS-based proteomics—data-dependent acquisition (DDA) and data-independent acquisition (DIA)—each present different benefits and drawbacks to the experimental design. In their recent paper, Prakash et al. (2014) present pSMART, a hybrid data Read the rest of this article
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