Limited Proteolysis with Targeted Proteomics Characterizes Protein Structure

Exploiting a feature of the protein characteristic under investigation, Feng et al. (2014) have developed a targeted proteomics workflow for large-scale investigation of structural changes.1 The scientists used a limited proteolysis strategy for initial protein digestion, then completed their proteomic analysis with selected reaction monitoring (SRM)-based quantitation. Protein function is a key regulator of protein Read the rest of this article

The post Limited Proteolysis with Targeted Proteomics Characterizes Protein Structure appeared first on Accelerating Science.

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