Serum Proteomics for Scrapie Biomarker Investigation

Scrapie, a transmissible spongiform encephalopathy affecting sheep, is a fatal neurodegenerative disease. As the disease progresses, normal brain prion proteins (PrPC) convert into protease-resistant isoforms (PrPSC), and the clinical signs of ataxia, pruritus and wasting develop. Although there is no evidence of direct transmission to humans, laboratory species such as rats and mice are susceptible Read the rest of this article

The post Serum Proteomics for Scrapie Biomarker Investigation appeared first on Accelerating Science.


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