Hyperuricemia and Endothelial Damage

Elevation of circulating uric acid levels (hyperuricemia) can arise from kidney dysfunction, among other causes. Hyperuricemia is known to cause endothelial damage, although the exact mechanism has not been fully elucidated. Recently, Zhang and colleagues used a proteomics technique, stable isotope labeling by amino acids in cell culture (SILAC), to explore the response of human Read the rest of this article

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